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You can set it by selecting V-Ray GPU from the Renderer dropdown dropdown when the Target drop-down is set to Production Rendering Mode from the top of the Render Setup window, or also by adjusting the selected renderer to V-Ray GPU in the Production setting found in the Assign Renderer rollout at the bottom of the Common tab. The main differences are that the IPR mode is interactive and the Production Rendering Mode is not. Production rendering allows you to render animations, and V-Ray calculates and uses Light Cache for GPU GI calculations if it has been set as secondary GI engine. For IPR, V-Ray GPU always uses Brute Force for both primary and secondary GI engine, unless Light Cache is used from file.

How do I use Light Cache with GPU?

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